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griseofulvin will lessen the extent or result of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.butabarbital will decrease the extent or result of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.enzalutamide will lessen the level or impact of diazepam by affecting hepati